Research Interest

Dr Sabahat Naeem completed her graduation and got a degree in Pharm D in 2008 from the University of Karachi. She was awarded PhD in Pharmaceutical Chemistry from the Faculty of Pharmacy at the University of Karachi in 2016. She joined Dow College of Pharmacy (DUHS) as a lecturer in 2009 and was later appointed as an Assistant Professor in the same college in the Department of Pharmaceutical Chemistry in 2018. Apart from teaching undergraduate and postgraduate students, she was also a lab incharge, mentor, and member of the QMS team at DCOP. Her research areas are designing and synthesis of compounds with medicinal values.

Drug Designing and Development

In-silico Drug Designing

Synthesis of medicinally important molecules (derivatives)

Determination of physico-chemical parameters of synthetic analogs

Research Publications

 •    Virtual screening, Molecular Docking study, characterization, and In-vitro Antibacterial evaluation of Piperazine derivatives Faisal Muhammad Khan, Sabahat Naeem, Saman Usmani, Mahwish Akhtar, Shamim Akhtar, Wajiha Gul (2022). RADS Journal of Pharmacy and Pharmaceutical Sciences, 10(4): 125-136.
•    In-silico determination of pKa and logP values of some synthetic analogues of isoniazid using Marvin software. Sabahat Naeem, Shamim Akhtar, Shaista Zafar, Sadia Iqbal (2020). Pakistan Journal of Pharmaceutical Sciences, 33(2): 715-719.

•    Synthesis, Characterization and Antimicrobial Activity of Piperidine Derivatives. Shaista Zafar, Shamim Akhtar, Syed Imran Ali, Nausheen Mushtaq, Sabahat Naeem, Mohsin Ali (2019). Journal of Chemical Society of Pakistan, 41(2): 363-367.

•    Development of new Isonicotinic acid hydrazide derivatives for the treatment of Depression. Sabahat Naeem, Shamim Akhtar, Shaista Zafar, Arfa Akram (2018). Hamdard Medicus, 61(2): 28-33.

•    Pharmacophoric Screening of Newly Synthesized Isoniazid Derivatives and their Antimycobacterial Activity. Sabahat Naeem, Shamim Akhtar, Zaheer Ali, Muhammad Yahya Noori, Ahsaan Ahmed (2018). Pakistan Journal of Pharmaceutical Sciences, 31(2): 567-573.
•    Cytotoxic and acute toxicity Studies of Isoniazid Derivatives. Sabahat Naeem, Shamim Akhtar, Zi-Ning Lei, Kimberly Lu, Shaista Zafar, Ahsaan Ahmed, Mohsin Ali, Mansoor Ahmed and Zhe-Sheng Chen (2017). Pakistan Journal of Pharmaceutical Sciences, 30(6)(Suppl): 2411-2415.
•    Synthesis, characterization and antimicrobial studies of novel pyridine quaternary analogs. Sabahat Naeem, Shamim Akhtar, Nousheen Mushtaq, Shaista Zafar and Muhammad Arif (2016). World Journal of Pharmaceutical Research, [Internet]; 5(7): 160-170. Available from: http://www.wjpr.net/dashboard/abstract_id/5394.
•    Antimicrobial and Antioxidant screening of Nʹ-substituted sulphonyl and benzoyl derivatives of 4-Pyridine carboxylic acid hydrazide. Sabahat Naeem, Shamim Akhtar, Nadia Asghar, Sikander Khan Sherwan, Nousheen Mushtaq, Arfa Kamil, Shaista Zafar, Muhammad Arif and Z.S. Saify (2015). Pakistan Journal of Pharmaceutical Sciences, 28(6): 2129-2134.
•    Antimalarial and Insecticidal activities of newly synthesized derivatives of Benzimidazole.
Arfa Kamil, Shamim Akhtar, Maryam Ahmed, Ghazala H. Rizwani, Sohail Hassan, Sabahat Naeem, Sarwat Jahan, Raheela khursheed and Hina Zahid (2015). Pakistan Journal of Pharmaceutical Sciences, 28(6): 2179-2184.
•    The structural modification causes the enhancement of analgesic activity of 4-(4′ chloro – phenyl)-4- hydroxy piperidine.
Kiran Rafiq, Zafar Saeed Saify, Rana Kausar, Najia Rahim, and Sabahat Naeem (2014). Asian Journal of Pharmaceutical and Clinical Research, 7(1)(Suppl): 99-101.
•    Synthesis and pharmacological evaluation of novel Benzoyl derivatives of Piperidine-4-carboxamide. Azra Rauf, Shamim Akhtar, Sabahat Naeem, Nousheen Mushtaq and Muhammad Arif (2014). International Journal of Research in Pharmacy and Chemistry, [Internet]; 4(3): 509-516. Available from: http://www.ijrpc.com/files/03-4120.pdf.
•    Synthesis of novel derivatives of 4-Pyridine carboxylic acid hydrazide and their activity on the central nervous system. Sabahat Naeem, Shamim Akhtar, Nousheen Mushtaq, Arfa kamil, Shaista Zafar, Sana Anwar and Muhammad Arif (2014). Pakistan Journal of Pharmaceutical Sciences, 27(5)(Special): 1401-1408.

Others

Service Activity

 •    Academic Responsibilities
•    Teaching of Undergraduate (Pharm.D.) courses
•    Pharmaceutical Organic Chemistry [Theory]
•    Pharmaceutical Instrumentation [Theory]
•    Medicinal Chemistry [Theory]
•    Pharmaceutical Mathematics [Theory]
•    Biostatistics [Theory]
•    Pharmaceutical Organic Chemistry [Lab]
•    Pharmaceutical Instrumentation [Lab]
•    Medicinal Chemistry [Lab]
•    Teaching of Post-Graduate (M.Phil.) Course
•    Instrumentation and Research Techniques [Theory]-(2020)

•    Administrative Responsibilities
•    Member of QMS-team (May 2017 – onwards)
•    Student Mentor (2013 – Onwards)
•    Lab-Incharge of Pharmaceutical Chemistry Laboratory (2015 - onwards)

Other Research or Creative Accomplishments

•    Project presentation in 7th All Pakistan DUHS-DICE Health Innovation Exhibition-2022 on the topic of “MIRACULOUS HERBAL TEA”. 
•    Project presentation in DUHS-DICE-2019 on the topic of “Development of Neutraceutical Ice cream”.
•    Project presentation in DUHS-DICE-2019 on the topic of “New Herbal syrup for Cough”.

Selected Professionals Presentations

•    Oral presentation in International Conference on Advances in Biological Sciences (ICABS-2023) held on March 2023 at University of Punjab, on the topic of “Insight into Molecular Interaction of Synthetic                     Benzimidazole Analogues for Anxiolytic Activity; an In-Silico Approach”.
•    Oral presentation in 2nd National Conference and E-poster presentation Innovation and Pharmacotherapy and Disease Management held on December 2020 at Jinnah Sindh Medical University.
•    Oral presentation in 1st International Conference Research Perspectives in Pharmaceutical Sciences-2019 at Hamdard University, on the topic of “Nanoencapsulation of Novel Bioactive derivatives of Isoniazid”.
•    Oral presentation in 1st International Conference Research Perspectives in Pharmaceutical Sciences-2019 at Hamdard University, on the topic of “Synthesis of some new synthetic phenacyl derivatives of                   Isonipecotamide as antimicrobial agents”.
•    Poster presentation in ICRIPS-2019 at Riphah International University, on the topic of “Computational Approach: Designing of Gemifloxacin Derivatives by In-silico Parameter”.
•    Poster presentation in 8th Annual Research Day-2017 at Dow International Medical College, Dow University of Health Sciences (DUHS) on the topic “Pharmacophoric