Research Interest

My research explores population dynamics using molecular techniques like ELISA, PCR, rtPCR, sequence analysis, and genetic expression studies. Through these methods, I aim to uncover the genetic variation within populations and its impact on phenotypic traits. Using PCR and rtPCR, I identify genetic markers associated with traits or diseases across diverse populations. Sequence analysis helps understand the genetic architecture underlying phenotypic diversity, including SNPs. Integrating molecular biology and population studies, my work contributes to understanding population genetics, molecular epidemiology, and the interplay between genetic variation and phenotypic expression.

https://orcid.org/0000-0002-2011-8810 

Research Publications

• Amir QU, Hanif F, Washdev W, Bilwani F, Usman Simjee S. Synonymous   polymorphism rs201256011 in dopamine receptor type 2 gene is associated with schizophrenia and PANSS score in Pakistani population: a first report. International Journal of Clinical Practice. 2020 Sep;74(9):e13536.

• Hanif F, Amir Q, Washdev W, Bilwani F, Simjee SU, Haque Z. A Novel Variant in Dopamine Receptor Type 2 Gene is Associated with Schizophrenia. Archives of Medical Research. 2021 Apr 1;52(3):348-53.

• Javed L, Hanif F, Malhi SM, Zaman U, Jahan N, Amir Q, Javed A, Malik AB, Abrar H. Diclofenac sodium enhances the antiepileptic effect of levetiracetam in pilocarpine induced epileptic mice model. Pakistan Journal of Pharmaceutical Sciences. 2021 Sep 2;34.

• Javed A, Malik AB, Amir Q, Hanif F, Washdev W, Jawed L. Glutamate ionotropic receptor AMPA type subunit 1 gene polymorphism (gly>ser) and its association with schizophrenia in Pakistani population: A pilot study. IJEHSR. 2021 Oct

• Hussain IS, Noor T, Amir Q, Washdev W, Hanif F. Prevalence of misconceptions and presentation of covid-19 post-vaccination symptoms among health care workers of karachi, pakistan. Journal of Pakistan Psychiatric Society. 2022 Oct 31;19(02).

• Zaheer S, Amir Q, Waseem HF, Riaz K, Zehra N, Shakil S, Shoaib M. Patterns of musculoskeletal disorders in health care providers and their association with ergonomic risks. International Journal of Occupational Safety and Ergonomics. 2023 Jan 6:1-9.

• Hanif F, Amir Q, Washdev W. Effect of DIO2 Gene Polymorphism on Thyroid Hormone Levels and Its Correlation with the Severity of Schizophrenia in a Pakistani Population. International Journal of Molecular Sciences. 2024; 25(3):1915. https://doi.org/10.3390/ijms25031915

• Irshad Bibi, Farina Hanif, Quratulain Amir, Washdev Washdev, & Mohammad Furqan Bari. (2024). Impact of Brain derived Neurotrophic factor gene polymorphism on its peripheral levels in schizophrenic patients. Journal of the Pakistan Medical Association, 74(2), S19–S. https://doi.org/10.47391/JPMA-DUHS-S05

Others

Oral Presentations:

• At 1st International Conference of Biomedical Sciences, at Dow University of Health Sciences, 20th -21st  March, 2023 on Effect of dio2 gene polymorphism on thyroid hormone Levels and their relationship with disease severity in
• Schizophrenia patients

• at 9th Annual Neuroscience Conference organized by organized by the Pakistan Society of Basic & Applied Neuroscience (PASBAN) in collaboration with the Department of Biochemistry, University of Karachi, August 2023 on Single Nucleotide Polymorphism in Iodothyronine deiodinase 2 gene and their association with thyroid hormone levels in schizophrenia patients in Pakistani population
• Oral presentation at 1st International conference on Biomedical sciences; Bridging Basic and Translational Research, organized by Institute of Biomedical sciences, Dow University of health sciences,  2023 on To investigate the potential contribution of Iodothyronine deiodinase 2 gene polymorphism in the pathophysiology of Schizophrenia and implication in therapeutic strategies
• Oral presentation at 2nd PROBE: Molecules to Mechanism, organized by Dept. Of Physiology, University of Karachi, 2020 on Polymorphisms in Exon 7 of Dopamine Receptor Type 2 gene and their association with schizophrenia in Pakistani population

Poster Presentation

•         1st award for poster presentation on (Association of Dopamine Receptor Type 2 gene       variant (Ser311Cys) with schizophrenia in Pakistani population: a case-control study) at 5th Annual Neuroscience Conference, 2019 held at Aga Khan University, Karachi 

•        Poster presentation at 7th International Symposium cum training Course on Molecular Medicine and Drug Research, 2019 held at PCMD on (Genetic Variability of Dopamine Receptor Type 2 in Schizophrenic Patients of Pakistan: A Case-Control Study)

•        Poster presentation at International Conference of Applied Biosciences 2019, held at Muhammad Ali Jinnah University on (Association of Dopamine Receptor Type 2 Gene Variants with Schizophrenia in Pakistani Population: A First Report)